Characterization of czcA, a gene involves in heavy metal resistance in Acinetobacter sp. ADP1 (Record no. 16406)

MARC details
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fixed length control field 03481nas|a2200397 a 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260817172523.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 071112s2007 th uu|m rtt 0| a1eng d
035 ## - SYSTEM CONTROL NUMBER
System control number .b11890952
099 #9 - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number AIT Thesis no.EV-07-26
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Monta Thammasatta
245 10 - TITLE STATEMENT
Title Characterization of czcA, a gene involves in heavy metal resistance in Acinetobacter sp. ADP1
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Pathum Thani, Thailand :
Name of publisher, distributor, etc. Asian Institute of Technology,
Date of publication, distribution, etc. 2007
300 ## - PHYSICAL DESCRIPTION
Extent 59 leaves :
Other physical details ill.
490 1# - SERIES STATEMENT
Series statement Thesis ;
Volume/sequential designation no. EV-07-26
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Asian Institute of Technology - Chulabhorn Research Institute - Mahidol University, 2007
520 ## - SUMMARY, ETC.
Summary, etc. Metals contaminated in the environnment have become important environmental pollutants and effect in soil, water and ground water. Acinetohacter sp. ADP1 was chosen in this study because it is common in soil and water. This study can be applied for the bio-indicator or as decomposer(s) when other microbes can not survive. Acinetohacter sp. ADP 1 has adaptive and cross protection responses when induced with 1OOuM zinc chloride and 25M cadmium chloride, indicating that ADPI contain genes responsible for zinc and cadmium resistance. However, no adaptive occurred when induce with 75M cobalt chloride. The cross protection response toward cobalt was also not occurred with zinc and cadmium induced cells. The czcA gene is the largest part of CzcCBA efflux pump system, which was proposed to be the cation efflux system that response to zinc, cobalt and cadmium. The czcA mutant strain was constructed and the result showed that the czcA mutant strain showed highly sensitive phenotype when cell were exposed to lethal concentrations of zinc, cobalt and also cadmium. This result strongly suggested that czcA gene plays a major role in the heavy metals resistance in Acinetobacter sp. ADP 1. Supporting the role of czcA in metal resistance, its transcription was up-regulated in the presence of zinc and cadmium. However, the czcA mutant remained most of adaptive and cross protection responses found in wild type, but at low level. This result provides an evidence for additional metal resistance determination in Acinetobacter sp. ADP 1.
500 ## - GENERAL NOTE
General note A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Environmental Engineering and Management Inter-University Program on Environmental Toxicology, Technology and Management.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Acinetobacter
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Heavy metals
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mayuree Fuangthong,
Relator term Chairperson
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Skorn Mongkolsuk,
Relator term Examination Committee
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Preeda Pakpian,
Relator term Examination Committee
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Chulabhom Research Institute/ Mahidol University/Asian Institute of Technology (CRI-MU-AIT),
Relator term Scholarship donor
810 2# - SERIES ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Asian Institute of Technology.
Title of a work Thesis ;
Volume/sequential designation no. EV-07-26
856 ## - ELECTRONIC LOCATION AND ACCESS
Materials specified Full-Text
Uniform Resource Identifier <a href="http://203.159.5.9/ait-thesis/detail.php?q=B10786">http://203.159.5.9/ait-thesis/detail.php?q=B10786</a>
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998 ## - LOCAL CONTROL INFORMATION (RLIN)
Operator's initials, OID (RLIN) 0
Cataloger's initials, CIN (RLIN) 071112
First date, FD (RLIN) m
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945 ## - LOCAL PROCESSING INFORMATION (OCLC)
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945 ## - LOCAL PROCESSING INFORMATION (OCLC)
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942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type 22-AIT Thesis (Replacement)
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type 40-Archives
909 ## - LOCAL ITEMS USED
Barcode Barcode : 30050120743405
CREATED CREATED : 2014-02-13
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Barcode Barcode : 30050160049655
CREATED CREATED : 2016-05-30
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      Available for Loans Asian Institute of Technology Library Asian Institute of Technology Library AIT Publications 17/08/2026 50.00   AIT Thesis no.EV-07-26 30050120743405 17/08/2026 3 17/08/2026 22-AIT Thesis (Replacement)
      Available for Loans Asian Institute of Technology Library Asian Institute of Technology Library Archives 17/08/2026     AIT Thesis no.EV-07-26 30050160049655 17/08/2026   17/08/2026 40-Archives
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