AI SearchChitosan microcapsules and chitosan membrane for drug delivery systems (Record no. 17092)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04310nas|a2200445 i 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260817172702.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200499s1998 th uzm rtt 00| a1eng d |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | .b11745654 |
| 099 #9 - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | AIT Thesis no. BP-98-12 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Anal, Anil Kumar |
| 245 10 - TITLE STATEMENT | |
| Title | Chitosan microcapsules and chitosan membrane for drug delivery systems |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Bangkok : |
| Name of publisher, distributor, etc. | Asian Institute of Technology, |
| Date of publication, distribution, etc. | 1998 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 78 leaves |
| 490 1# - SERIES STATEMENT | |
| Series statement | Thesis ; |
| Volume/sequential designation | no. BP-98-12 |
| 500 ## - GENERAL NOTE | |
| General note | A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science, School of Environment, Resources and Development |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Asian Institute of Technology, 1998 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In this study, both chitosan beads and chitosan membrane have been investigated for applications in systems of controlled release of phaimaceuticals. Chitosan beads can be prepai-ed by microencapsulation of chitosan droplets. Microencapsulation comprises various technologies that can be used to coat small particles of solid or droplets of liquid dispersion with a thin coating layer. The dropping of dissolved chitosan into a solution of tripolyphosphate (TPP) leads instantaneously to the formation of beads by ionotropic gelation without using any sophisticated instruments. Conditions of microencapsulation have been investigated to optimize bead formation and entrapment of the model protein, bovine serum albumin (BSA). The speed of droppings, a slight stirring speed of TPP solution, 5-7 cm dropping distance from the surface of TPP solution and the type, concentration, and viscosity of chitosan solution were fotmd the major influensive parameters to form smooth and spherical chitosan beads. Crosslinking between chitosan and TPP occurs within 15 minutes. The pH 7.2 ofTPP was found the optimum pH for the maximum entrapment of bovine serum albumin (BSA), which was used as model drug for this study. The degree of deacetylation of chitosan showed an influensive on the entrapment of BSA while the concentration ofTPP, viscosity of chitosan solution ai1d more than 3% load of BSA did not have any effect. The chitosan beads/microcapsules were found to swell in acidic medium (0.1 N HCl). The release of BSA from the chitosan microcapsules was found depending upon the pH of the dissolution medium, drying condition, and the type of chitosan. Chitosan membrane prepared from chitosan with a 95% degree of deacetylation showed similar behavior as of commercially available cellulose membrane. The equilibrium dialysis for all model drugs aspirin, phenobarbitone Na salt, and Sulfanilamide occurred within two hours in both cellulose and chitosan membranes. The fraction of unbound drugs could be determined by using chitosan membrane. The unbound fractions of drugs obtained by using commercial regenerated cellulose membrane were comparable with those obtained by using chitosan membrane. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chitosan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stevens, Willem Frans, |
| Relator term | Chairperson |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Korbtham Sathirakul, |
| Relator term | Examination committee |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Suwalee Chandrkrachang, |
| Relator term | Examination committee |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rakshit, Sudip Kumar, |
| Relator term | Examination Committee |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Montet, Didier, |
| Relator term | Examination committee |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pakorn Nuchnoi, |
| Relator term | Examiantion Committee |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Government of Austria, |
| Relator term | Scholarship donor |
| 810 2# - SERIES ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Asian Institute of Technology. |
| Title of a work | Thesis ; |
| Volume/sequential designation | no. BP-98-12 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | Full-Text |
| Uniform Resource Identifier | <a href="http://203.159.5.9/ait-thesis/detail.php?q=B13238">http://203.159.5.9/ait-thesis/detail.php?q=B13238</a> |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) | |
| a | .b11745654 |
| b | mnait |
| c | y |
| 902 ## - LOCAL DATA ELEMENT B, LDB (RLIN) | |
| a | 240411 |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) | |
| Operator's initials, OID (RLIN) | 0 |
| Cataloger's initials, CIN (RLIN) | 990421 |
| First date, FD (RLIN) | m |
| -- | a |
| -- | y |
| -- | 0 |
| 945 ## - LOCAL PROCESSING INFORMATION (OCLC) | |
| l | mnait |
| 945 ## - LOCAL PROCESSING INFORMATION (OCLC) | |
| l | mnait |
| 945 ## - LOCAL PROCESSING INFORMATION (OCLC) | |
| l | mnarc |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | 20-AIT Publication |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | 40-Archives |
| 909 ## - LOCAL ITEMS USED | |
| Barcode | Barcode : 30050120683395 |
| CREATED | CREATED : 1997-11-22 |
| RECORD Id | RECORD # : i12129112 |
| LPATRON | LPATRON : 1021929 |
| LCHKIN | LCHKIN : 2010-08-08 |
| RENEWALS | # RENEWALS : 0 |
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| -- | IUSE3 : 1 |
| -- | TOT CHKOUT : 14 |
| -- | TOT RENEW : 3 |
| 909 ## - LOCAL ITEMS USED | |
| Barcode | Barcode : 30050120683437 |
| CREATED | CREATED : 1997-11-22 |
| RECORD Id | RECORD # : i12129124 |
| LPATRON | LPATRON : 1025322 |
| LCHKIN | LCHKIN : 2018-04-29 |
| RENEWALS | # RENEWALS : 0 |
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| -- | TOT CHKOUT : 17 |
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| 909 ## - LOCAL ITEMS USED | |
| Barcode | Barcode : 30050120351225 |
| CREATED | CREATED : 2016-10-06 |
| RECORD Id | RECORD # : i13029125 |
| LPATRON | LPATRON : 0 |
| LCHKIN | LCHKIN : - |
| RENEWALS | # RENEWALS : 0 |
| -- | # OVERDUE : 0 |
| -- | IUSE3 : 0 |
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| Withdrawn status | Lost status | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Barcode | Date last seen | Copy number | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Available for Loans | Asian Institute of Technology Library | Asian Institute of Technology Library | AIT Publications | 17/08/2026 | AIT Thesis no. BP-98-12 | 30050120683395 | 17/08/2026 | 1 | 17/08/2026 | 20-AIT Publication | ||||
| Available for Loans | Asian Institute of Technology Library | Asian Institute of Technology Library | AIT Publications | 17/08/2026 | AIT Thesis no. BP-98-12 | 30050120683437 | 17/08/2026 | 2 | 17/08/2026 | 20-AIT Publication | ||||
| Available for Loans | Asian Institute of Technology Library | Asian Institute of Technology Library | Archives | 17/08/2026 | AIT Thesis no. BP-98-12 | 30050120351225 | 17/08/2026 | 17/08/2026 | 40-Archives |