AI SearchControlled release of drugs from chitosan membrane and gel (Record no. 23199)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03499nas|a2200409 i 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260818085123.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 030418s2002 th uzm rtt 00| a1eng d |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | .b11880788 |
| 099 #9 - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | AIT Thesis no. BP-02-07 |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sirikanya Vibhasiri |
| 245 10 - TITLE STATEMENT | |
| Title | Controlled release of drugs from chitosan membrane and gel |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Bangkok : |
| Name of publisher, distributor, etc. | Asian Institute of Technology, |
| Date of publication, distribution, etc. | 2002 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 82 leaves |
| 490 1# - SERIES STATEMENT | |
| Series statement | Thesis ; |
| Volume/sequential designation | no. BP-02-07 |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Asian Institute of Technology, 2002 |
| 500 ## - GENERAL NOTE | |
| General note | A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science, School of Environment, Resources and Development |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Chitosan matrix system in the form of membrane and semi-solid gel was in vestigated for appli cation in controlled drug deli very system. In this study, two chitosan samples differing in degree of deacetylation (69% and 89%DD) prepared from shrimp chitin were used. The chitosan membranes were prepared by a casting technique using acetic acid as a solvent. The membranes were characterized in the forms of swelling index and permeability behavior of the model drugs (lidocaine hydrochloride and progesterone). The lesser swelling index and more sustained permeation were found with the membrane prepared from 89% DD in compare to membrane prepared from 69% DD chitosan. Drug loaded membranes were prepared and studied for the release pattern. The membranes were th in, transparent and homogenous. The fast release pattern was observed in the initial first hour, whereas the drug release showed more sustained in the later hours depending on the types of chitosan membranes used. More sustained release was obtained with the membrane prepared from higher %DD. In addition, it was observed that release of drug could be controlled by using rate controlled chitosan membrane as permeation barrier screened on the drug loaded membrane. N-acetylchitosan gels were prepared by acetylation of chitosan with acetic anhydride. The semi-solid gels were transparent and elastic. The gel can be exploited as a drug reservoir and as controlled release drug carrier. The rate of drug release was constant within the first hour from lidocaine hydrochloride loaded gel, and up to six hours from progesterone loaded gel. Sustained release of drug was obtained with the use of Nacetylchitosan membrane as rate controlled device. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chitosan |
| General subdivision | Controlled release |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drugs |
| General subdivision | Controlled release |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stevens, Willem Frans, |
| Relator term | Chairperson |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Suwalee Chandrkrachang, |
| Relator term | Examination Committee |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Preeda Pakpian, |
| Relator term | Examination Committee |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Korbtham Sathirakul, |
| Relator term | Examination Committee |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Royal Thai Govenment, |
| Relator term | Scholarship Donor |
| 810 2# - SERIES ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Asian Institute of Technology. |
| Title of a work | Thesis ; |
| Volume/sequential designation | no. BP-02-07 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | Full-Text |
| Uniform Resource Identifier | <a href="http://203.159.5.9/ait-thesis/detail.php?q=B08087">http://203.159.5.9/ait-thesis/detail.php?q=B08087</a> |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) | |
| a | .b11880788 |
| b | mnait |
| c | u |
| 902 ## - LOCAL DATA ELEMENT B, LDB (RLIN) | |
| a | 240403 |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) | |
| Operator's initials, OID (RLIN) | 0 |
| Cataloger's initials, CIN (RLIN) | 030418 |
| First date, FD (RLIN) | m |
| -- | a |
| -- | u |
| -- | 0 |
| 945 ## - LOCAL PROCESSING INFORMATION (OCLC) | |
| l | mnait |
| 945 ## - LOCAL PROCESSING INFORMATION (OCLC) | |
| l | mnarc |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | 22-AIT Thesis (Replacement) |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | 40-Archives |
| 909 ## - LOCAL ITEMS USED | |
| Barcode | Barcode : 30050120682900 |
| CREATED | CREATED : 2013-06-09 |
| RECORD Id | RECORD # : i12739911 |
| LPATRON | LPATRON : 0 |
| LCHKIN | LCHKIN : - |
| RENEWALS | # RENEWALS : 0 |
| -- | # OVERDUE : 0 |
| -- | IUSE3 : 0 |
| -- | TOT CHKOUT : 0 |
| -- | TOT RENEW : 0 |
| 909 ## - LOCAL ITEMS USED | |
| Barcode | Barcode : 30050120350623 |
| CREATED | CREATED : 2016-10-06 |
| RECORD Id | RECORD # : i13030139 |
| LPATRON | LPATRON : 0 |
| LCHKIN | LCHKIN : - |
| RENEWALS | # RENEWALS : 0 |
| -- | # OVERDUE : 0 |
| -- | IUSE3 : 0 |
| -- | TOT CHKOUT : 0 |
| -- | TOT RENEW : 0 |
| Withdrawn status | Lost status | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Cost, normal purchase price | Total checkouts | Full call number | Barcode | Date last seen | Copy number | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Available for Loans | Asian Institute of Technology Library | Asian Institute of Technology Library | AIT Publications | 18/08/2026 | 50.00 | AIT Thesis no. BP-02-07 | 30050120682900 | 18/08/2026 | 3 | 18/08/2026 | 22-AIT Thesis (Replacement) | ||||
| Available for Loans | Asian Institute of Technology Library | Asian Institute of Technology Library | Archives | 18/08/2026 | AIT Thesis no. BP-02-07 | 30050120350623 | 18/08/2026 | 18/08/2026 | 40-Archives |