AI SearchAntifungal activity of probiotics and their metabolites and elucidation of the mechanism of interaction (Record no. 6271)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 04028nas a2200445 a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260817162759.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211006s2021 th uu m rtt 0| a1eng |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | .b12373540 |
| 099 #9 - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | AIT Thesis no.FB-21-04 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Pant, Krisha |
| 245 10 - TITLE STATEMENT | |
| Title | Antifungal activity of probiotics and their metabolites and elucidation of the mechanism of interaction |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Pathum Thani, Thailand : |
| Name of publisher, distributor, etc. | Asian Institute of Technology, |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 126 leaves : |
| Other physical details | ill. |
| 490 1# - SERIES STATEMENT | |
| Series statement | Thesis ; |
| Volume/sequential designation | no.FB-21-04 |
| 500 ## - GENERAL NOTE | |
| General note | A thesis submitted in partial fulfillment of the requirements for the degree of Master of Engineering in Food Engineering and Bioprocess Technology, School of Environment, Resources and Development |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M. Eng.) - Asian Institute of Technology, 2021 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Food contamination by Aspergillus and the toxic metabolites produced by them have been known to cause food safety issues and has been recently countered by biocontrol methods using Lactobacillus. This study was carried out to evaluate the inhibitory interaction between fungi Aspergillus niger and live Lactobacillus cell and elucidate the antifungal mechanism of action by partially purified Lactobacillus extract. Further, the applicability of these extract with chitosan was observed in table grapes and chicken patties in-terms of coatings and antimicrobial films respectively. There was significant reduction in the viability (1 log reduction) and biomass (55.15%) of fungi by both Lactobacillus cells. The mechanism of inhibitory action by L. casei was found to be by increasing the permeance of cell wall of fungi by interaction with the cell wall and cell membranes by the process of cell leakage from fungi causing changes in the morphology like hollowing/flattening of hyphae, visualized through SEM. In contrast to that, Lactobacillus plantarum was found to inhibit fungal cell growth by mechanism other than interaction with both cell wall and cell membrane as observed through sorbitol and ergosterol assay. Strong antifungal activities of L. casei extract with chitosan were detected as coating (3 log reduction) and films (2.84 log reduction) in both grapes and chicken respectively due to synergistic antifungal action FICindex (<1) by the hydrogen bonding and electrostatic interaction observed by FTIR analysis. Addition of antifungal extract from L. casei was found to disrupt the bonding between and within the the long chain chitosan molecules in the film, changing its mechanical properties (tensile stress (MPa), elongation at break, EB%) and making it more susceptible to water permeability, increased thickness, swelling index. This susceptibility was encountered by crosslinking the chitosan by phosphate salts. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Probiotics |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Metabolites |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chitosan |
| General subdivision | Biotechnology |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Anal, Anil Kumar, |
| Relator term | Chairperson |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Loc Thai Nguyen, |
| Relator term | Co-Chairperson |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Datta, Avishek, |
| Relator term | Examination Committee |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Bangchak Petroleum Public Company Limited, Thailand, |
| Relator term | Scholarship Donor |
| 810 2# - SERIES ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Asian Institute of Technology. |
| Title of a work | Thesis ; |
| Volume/sequential designation | no.FB-21-04 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | Full-Text |
| Uniform Resource Identifier | <a href="http://203.159.5.9/ait-thesis/detail.php?q=B14883">http://203.159.5.9/ait-thesis/detail.php?q=B14883</a> |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) | |
| a | .b12373540 |
| b | mnarc |
| c | m |
| 902 ## - LOCAL DATA ELEMENT B, LDB (RLIN) | |
| a | 240418 |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) | |
| Operator's initials, OID (RLIN) | 0 |
| Cataloger's initials, CIN (RLIN) | 211006 |
| First date, FD (RLIN) | m |
| -- | b |
| -- | m |
| -- | 0 |
| 945 ## - LOCAL PROCESSING INFORMATION (OCLC) | |
| l | mnait |
| 945 ## - LOCAL PROCESSING INFORMATION (OCLC) | |
| l | mnarc |
| 945 ## - LOCAL PROCESSING INFORMATION (OCLC) | |
| l | mnarc |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | 40-Archives |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | 67-Electronic Resource |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | 20-AIT Publication |
| 909 ## - LOCAL ITEMS USED | |
| Barcode | Barcode : 30050120885438 |
| CREATED | CREATED : 2021-04-10 |
| RECORD Id | RECORD # : i13351692 |
| LPATRON | LPATRON : 0 |
| LCHKIN | LCHKIN : - |
| RENEWALS | # RENEWALS : 0 |
| -- | # OVERDUE : 0 |
| -- | IUSE3 : 0 |
| -- | TOT CHKOUT : 0 |
| -- | TOT RENEW : 0 |
| 909 ## - LOCAL ITEMS USED | |
| Barcode | Barcode : - |
| CREATED | CREATED : 2021-04-10 |
| RECORD Id | RECORD # : i13351709 |
| LPATRON | LPATRON : 0 |
| LCHKIN | LCHKIN : - |
| RENEWALS | # RENEWALS : 0 |
| -- | # OVERDUE : 0 |
| -- | IUSE3 : 0 |
| -- | TOT CHKOUT : 0 |
| -- | TOT RENEW : 0 |
| 909 ## - LOCAL ITEMS USED | |
| Barcode | Barcode : 30050121023906 |
| CREATED | CREATED : 2022-12-16 |
| RECORD Id | RECORD # : i13420185 |
| LPATRON | LPATRON : 0 |
| LCHKIN | LCHKIN : - |
| RENEWALS | # RENEWALS : 0 |
| -- | # OVERDUE : 0 |
| -- | IUSE3 : 0 |
| -- | TOT CHKOUT : 0 |
| -- | TOT RENEW : 0 |
| Withdrawn status | Lost status | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Barcode | Date last seen | Copy number | Price effective from | Koha item type | Cost, normal purchase price |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Available for Loans | Asian Institute of Technology Library | Asian Institute of Technology Library | Archives | 17/08/2026 | AIT Thesis no.FB-21-04 | 30050120885438 | 17/08/2026 | 1 | 17/08/2026 | 40-Archives | |||||
| Available for Loans | Asian Institute of Technology Library | Asian Institute of Technology Library | Archives | 17/08/2026 | AIT Thesis no.FB-21-04 | 17/08/2026 | 17/08/2026 | 67-Electronic Resource | |||||||
| Available for Loans | Asian Institute of Technology Library | Asian Institute of Technology Library | AIT Publications | 17/08/2026 | AIT Thesis no.FB-21-04 | 30050121023906 | 17/08/2026 | 1 | 17/08/2026 | 20-AIT Publication | 50.00 |