03299nas|a2200421 i 4500 20260817172702.0 030418s2002 th uzm rtt 00| a1eng d .b11880752 AIT Thesis no. BP-02-04 Azad, Abul Kalam Chitosan membrane as a wound healing agent : characterization and clinical application Bangkok : Asian Institute of Technology, 2002 54 leaves Thesis ; no. BP-02-04 Thesis (M.Sc.) - Asian Institute of Technology, 2002 A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science, School of Environment, Resources and Development Chitosan, a derivative of chitin, has potential biomedical applications. For this study the suitability of chitosan membrane as wound dressing was compared with that of bactigras, a chlorhexidine acetate impregnated tulle gras wound closing material. Chitosan membrane was prepared from shrimp chitosan with a degree of deacetylation of 75 % or 88.5% and thickness of lOom or 30om. The membranes were sterilized by either ethylene oxide or y- radiation. Fresh skin graft donor site was used for dressing wounds that resulted at skin graft donor site after removal of the skin layer of 0.010-0.015 inch thickness using a dermatome. One half of the wound was dressed by chitosan membranes with different physico-chemical properties and other half by bactigras. The healing rate was compared by both clinical observation and histological examination. Digital images were taken at 0 and 10 postoperative days. Itching and pain sensitivity of the wound dressed area was scored for the first three days using a visual analogue scale. After 10 days chitosan dressed area was found to have healed more promptly than that was dressed using bactigras. Moreover, the chitosan membrane showed positive effect on granulation tissue formation. Reepithelialization occurred faster in case of chitosan membrane as compared to bactigras. These data confirm that chitosan membranes could be a potential substitute for wound dressing in the process of wound healing. Chitosan Wound healing Stevens, Willem Frans, Chairperson Suwalee Chandrkrachang, Examination Committee Preeda Pakpian, Examination Committee Niwet Sermsintham, Examination committee Korbtham Sathirakul, Examination Committee The Royal Netherlands Government, Scholarship Donor Asian Institute of Technology. Thesis ; no. BP-02-04 Full-Text http://203.159.5.9/ait-thesis/detail.php?q=B08081 .b11880752 mnait u 240403 0 030418 m a u 0 mnait mnarc 22 40 Barcode : 30050120682843 CREATED : 2013-06-09 RECORD # : i12739947 LPATRON : 0 LCHKIN : - # RENEWALS : 0 # OVERDUE : 0 IUSE3 : 0 TOT CHKOUT : 0 TOT RENEW : 0 Barcode : 30050120350953 CREATED : 2016-10-06 RECORD # : i13029447 LPATRON : 0 LCHKIN : - # RENEWALS : 0 # OVERDUE : 0 IUSE3 : 0 TOT CHKOUT : 0 TOT RENEW : 0 17090 17090 0 0 0 0 MAIN MAIN mnait 2026-08-17 50.00 0 AIT Thesis no. BP-02-04 30050120682843 2026-08-17 17:27:02 3 2026-08-17 22 0 0 0 0 MAIN MAIN mnarc 2026-08-17 0 AIT Thesis no. BP-02-04 30050120350953 2026-08-17 17:27:02 2026-08-17 40