03552nas a2200445 a 4500 20260818113205.0 110606s2010 th uu|m rtt 0| a1eng d .b12096295 AIT Diss. no.EV-10-04 Manaswee Arayasiri Exposure to 1,3-butadiene and its possible effects on temple workers and traffic policemen Pathum Thani, Thailand : Asian Institute of Technology, 2010 101 p. : ill. Dissertation ; no. EV-10-04 A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Engineering in Environmental Engineering and Management Inter-University Program on Environmental Toxicolog y, Technology and Management Thesis (Ph.D.) - Asian Institute of Technology - Chulabhorn Research Institute - Mahidol University, 2010 Study objectives were, first, to determine the poss ible health risk of temple workers and traffic policemen from 1,3-butadiene exposure b y using biomarkers of exposure and early biological effects, and evaluate confounding factors that may affect on these biomarkers, and second, to study the emission of 1, 3 butadiene from burning incense. 1,3- Butadiene concentrations in the temple and on the r oadsides were significantly larger than in the offices (P < 0.001). Temple workers and traf fic policemen were significantly more exposed to 1,3-butadiene than controls ( p < 0.001). The urinary 1,3-butadiene metabolite, monohydroxy-butenyl mercapturic acid levels in expo sed group were larger than those in controls. 8-Hydroxy -2{u2019}-deoxyguanosine in leukocyte s (8-OHdG), DNA strand breaks, and DNA repair capacity measured by increases in gamma ray induced chromosome aberration, used as biomarkers of early biological effects, have been measured and were significantly larger in exposed workers than contro l subjects. So, temple workers and traffic policemen who are exposed to 1,3-butadiene from burning incense and automobile emissions in their workplaces, are more vulnerable to develop diseases such as cancer than controls. Traffic police Health risk assessment Butadiene Mathuros Ruchirawat, Chairperson Preeda Pakpian, Examination Committee Autrup, Herman Examination committee Panida Navasumrit, Examination committee Chulabhorn Research Institute, Scholarship donor Mahidol University, Scholarship donor Asian Institute of Technology Fellowship, Scholarship donor Asian Institute of Technology. Dissertation ; no. EV-10-04 Full-Text http://203.159.5.9/ait-thesis/detail.php?q=B00560 .b12096295 mnait u 240403 0 110606 m a u 0 000:001:PDF:b1209629:000657:0:0:0:0:0:0 Abstract-AIT Diss. no.EV-10-04 n mnait mnarc 22 40 Barcode : 30050120553804 CREATED : 2012-08-21 RECORD # : i12687820 LPATRON : 0 LCHKIN : - # RENEWALS : 0 # OVERDUE : 0 IUSE3 : 0 TOT CHKOUT : 0 TOT RENEW : 0 Barcode : 30050160004098 CREATED : 2016-09-02 RECORD # : i12879186 LPATRON : 0 LCHKIN : - # RENEWALS : 0 # OVERDUE : 0 IUSE3 : 0 TOT CHKOUT : 0 TOT RENEW : 0 42559 42559 0 0 0 0 MAIN MAIN mnait 2026-08-18 0 AIT Diss. no.EV-10-04 30050120553804 2026-08-18 11:32:05 3 2026-08-18 22 0 0 0 0 MAIN MAIN mnarc 2026-08-18 0 AIT Diss. no.EV-10-04 30050160004098 2026-08-18 11:32:05 2026-08-18 40