TY  - SER
AU  - Manaswee Arayasiri
AU  - Mathuros Ruchirawat,
AU  - Preeda Pakpian,
AU  - Autrup,Herman
AU  - Panida Navasumrit,
ED  - Chulabhorn Research Institute,
ED  - Mahidol University,
ED  - Asian Institute of Technology Fellowship,
TI  - Exposure to 1,3-butadiene and its possible effects on temple workers and traffic policemen
T2  - Dissertation
PY  - 2010///
CY  - Pathum Thani, Thailand
PB  - Asian Institute of Technology
KW  - Traffic police
KW  - Health risk assessment
KW  - Butadiene
N1  - A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Engineering in Environmental Engineering and Management Inter-University Program on Environmental Toxicolog y, Technology and Management; Thesis (Ph.D.) - Asian Institute of Technology - Chulabhorn Research Institute - Mahidol University, 2010
N2  - Study objectives were, first, to determine the poss ible health risk of temple workers  and  traffic  policemen  from  1,3-butadiene  exposure  b y  using  biomarkers  of  exposure  and  early  biological  effects,  and  evaluate  confounding  factors  that  may  affect  on  these  biomarkers, and second, to study the emission of 1, 3 butadiene from burning incense. 1,3- Butadiene concentrations in the temple and on the r oadsides were significantly larger than  in  the  offices  (P  <  0.001).  Temple  workers and  traf fic  policemen  were  significantly  more  exposed to 1,3-butadiene than controls ( p  < 0.001).  The urinary 1,3-butadiene metabolite, monohydroxy-butenyl  mercapturic acid  levels in expo sed  group  were  larger  than  those  in  controls. 8-Hydroxy -2{u2019}-deoxyguanosine in leukocyte s (8-OHdG), DNA strand breaks, and  DNA   repair   capacity   measured   by   increases   in   gamma  ray   induced   chromosome  aberration,  used  as  biomarkers  of  early  biological  effects,  have  been  measured  and  were  significantly  larger  in  exposed  workers  than  contro l  subjects.  So,  temple  workers  and  traffic policemen who are exposed to 1,3-butadiene  from burning incense and automobile  emissions in their workplaces, are more vulnerable  to develop diseases such as cancer than  controls.
UR  - http://203.159.5.9/ait-thesis/detail.php?q=B00560
ER  -