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005			20260818113205.0
008			110606s2010 th uu|m rtt 0| a1eng d
035			_a.b12096295
099		9	_aAIT Diss. no.EV-10-04
100	0		_aManaswee Arayasiri
245	1	0	_aExposure to 1,3-butadiene and its possible effects on temple workers and traffic policemen
260			_aPathum Thani, Thailand : _bAsian Institute of Technology, _c2010
300			_a101 p. : _bill.
490	1		_aDissertation ; _vno. EV-10-04
500			_aA dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Engineering in Environmental Engineering and Management Inter-University Program on Environmental Toxicolog y, Technology and Management
502			_aThesis (Ph.D.) - Asian Institute of Technology - Chulabhorn Research Institute - Mahidol University, 2010
520			_aStudy objectives were, first, to determine the poss ible health risk of temple workers and traffic policemen from 1,3-butadiene exposure b y using biomarkers of exposure and early biological effects, and evaluate confounding factors that may affect on these biomarkers, and second, to study the emission of 1, 3 butadiene from burning incense. 1,3- Butadiene concentrations in the temple and on the r oadsides were significantly larger than in the offices (P < 0.001). Temple workers and traf fic policemen were significantly more exposed to 1,3-butadiene than controls ( p < 0.001). The urinary 1,3-butadiene metabolite, monohydroxy-butenyl mercapturic acid levels in expo sed group were larger than those in controls. 8-Hydroxy -2{u2019}-deoxyguanosine in leukocyte s (8-OHdG), DNA strand breaks, and DNA repair capacity measured by increases in gamma ray induced chromosome aberration, used as biomarkers of early biological effects, have been measured and were significantly larger in exposed workers than contro l subjects. So, temple workers and traffic policemen who are exposed to 1,3-butadiene from burning incense and automobile emissions in their workplaces, are more vulnerable to develop diseases such as cancer than controls.
650		0	_aTraffic police _xHealth risk assessment
650		0	_aButadiene
700	0		_aMathuros Ruchirawat, _eChairperson
700	0		_aPreeda Pakpian, _eExamination Committee
700	1		_aAutrup, Herman _eExamination committee
700	0		_aPanida Navasumrit, _eExamination committee
710	2		_aChulabhorn Research Institute, _eScholarship donor
710	2		_aMahidol University, _eScholarship donor
710	2		_aAsian Institute of Technology Fellowship, _eScholarship donor
810	2		_aAsian Institute of Technology. _tDissertation ; _vno. EV-10-04
856			_3Full-Text _uhttp://203.159.5.9/ait-thesis/detail.php?q=B00560
907			_a.b12096295 _bmnait _cu
902			_a240403
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962			_a000:001:PDF:b1209629:000657:0:0:0:0:0:0 _tAbstract-AIT Diss. no.EV-10-04 _vn
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