Analysis of MEMS based heparin infusion pump for wearable artificial kidney system (WAK)

By: Call Number: AIT Thesis no.ISE-10-33 Contributor(s): Material type: TextSeries: Asian Institute of Technology. Thesis ; no. ISE-10-33Publication details: Pathum Thani : Asian Institute of Technology, 2010Description: 58 p. : ill. (some col.), chartsSubject(s): Online resources: Dissertation note: Thesis (M.Eng.) - Asian Institute of Technology, 2010 Summary: Kidney failure is one of the major health problems around the world andincreasing continuously. The research forecastsan exponential growth in the kidney failureduring coming years.There are twoconventional treatments for end stage renal disease (ESRD) and acute renal failure (ARF) those are dialysis and inherent kidney transplant.After kidney transplant,the patient has to take expensive medicine for a long time.There are many limitations associated with the conventional treatment methods. To overcome the limitations of conventional treatment methods, MEMSbased hemodialysis machine or wearable artificial kidney (WAK) can beused.Themajor benefit of this technology is that thepatients can continue their work during dialysis. It isvery cheap and easy to operate.The basic objective of this research is to study the flow rate of available micropumps using different liquids (DI water, heparin, blood, etc) and find out the suitabledevice forwearable artificial kidney (WAK)or hemodialysis machine.The controlled electronic circuit is used to investigate the fluid flow rate through the micropump. The sine wave, rectangular wave and SRS signal have been used to operate the micropump. Numerical simulation of diaphragm of micropump has also been conducted using ANSYS tofind the deflection and stress distribution of membrane. This study gives useful information to develop the MEMSbased hemodialysis system.
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A thesis submitted in partial fulfillment of the requirements for the Degree of Master of ScienceinMechatronics, School of Engineering and Technology

Thesis (M.Eng.) - Asian Institute of Technology, 2010

Kidney failure is one of the major health problems around the world andincreasing continuously. The research forecastsan exponential growth in the kidney failureduring coming years.There are twoconventional treatments for end stage renal disease (ESRD) and acute renal failure (ARF) those are dialysis and inherent kidney transplant.After kidney transplant,the patient has to take expensive medicine for a long time.There are many limitations associated with the conventional treatment methods. To overcome the limitations of conventional treatment methods, MEMSbased hemodialysis machine or wearable artificial kidney (WAK) can beused.Themajor benefit of this technology is that thepatients can continue their work during dialysis. It isvery cheap and easy to operate.The basic objective of this research is to study the flow rate of available micropumps using different liquids (DI water, heparin, blood, etc) and find out the suitabledevice forwearable artificial kidney (WAK)or hemodialysis machine.The controlled electronic circuit is used to investigate the fluid flow rate through the micropump. The sine wave, rectangular wave and SRS signal have been used to operate the micropump. Numerical simulation of diaphragm of micropump has also been conducted using ANSYS tofind the deflection and stress distribution of membrane. This study gives useful information to develop the MEMSbased hemodialysis system.

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